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Dr. Rogelio Trevino, MD

Integrative Medicine and Medical Marijuana

Dr. Trevino was born in Los Angeles, California, and raised in Dallas, Texas. He completed his undergraduate studies at the University of Texas at Austin before pursuing his medical degree at the University of Monterrey in Mexico. Following medical school, Dr. Trevino specialized in Family Medicine through the University of Texas Health Science Center McAllen Program.

Dr. Trevino furthered his expertise by completing a one-year fellowship in Geriatric Medicine at The George Washington University in Washington, D.C. He then expanded his knowledge in integrative healthcare with a two-year fellowship in Complementary and Alternative Medicine at the University of Arizona in Tucson.

With a broad range of training in both traditional and alternative medical practices, Dr. Trevino is committed to providing holistic, patient-centered care that addresses the unique needs of each individual.

Dr. Trevino is a board-certified Family Medicine physician with over 25 years of experience in primary care. His clinical expertise is complemented by a strong background in research, particularly in addictive psychiatry, where he has contributed to the development of pharmacological treatments for substance use disorders. His work has included research on Naltrexone, Acamprosate, Bupropion, and Topiramate.

Dr. Trevino is certified by the American Society of Ketamine Physicians for the responsible use of ketamine in clinical settings. He also holds certifications in Advanced Cardiac Life Support (ACLS) and Pharmacogenomics, highlighting his commitment to evidence-based and personalized medicine.

He was honored as one of Austin Monthly’s Top Doctors in both Family Medicine and Geriatric Medicine in 2019, 2020, and 2021. In addition to his clinical and research roles, Dr. Trevino has been actively involved in professional leadership. He has served as Chairman and Delegate for the Texas Academy of Family Physicians and is a graduate of the organization’s Leadership Program.

Our Philosophy

Cannabis has a long history in the treatment of various diseases. Its medicinal use can be traced back to ancient Central Asia and Western China, with the earliest known documentation from around 2800 BC. This early reference appears in the pharmacopeia of Emperor Shen Nung, a pioneering figure in the development of Chinese medicine. There have been many well documented studies supporting the medicinal properties of Cannabis.

At the Texas Integrative Cannabis Clinic, we specialize in integrative cannabis medicine consultations to address various conditions recognized by the Texas Compassionate Use Program. While we believe in the significant therapeutic potential of cannabis, we also consider individual factors such as genetics, age, and existing health conditions that may impact treatment efficacy.

We are mindful of potential side effects and interactions with other medications. To optimize treatment, we also evaluate other cannabinoids and terpenes that might provide additional benefits and help reduce any adverse effects.

At TICC we offer over 20 years of experience in medicine and in 3 different specialties, Family Medicine, Geriatrics and Complementary and Alternative Medicine. Our formal academic training in three different disciplines of medicine allows us to have a good understanding of a person's unique health needs and how cannabis medicine may provide treatment to treatable conditions.

Human Cannabinoid Receptors
Human Cannabinoid Receptors

Cannabinoid Receptors and the Endocannabinoid System

The human body has several types of cannabinoid receptors—special sites where cannabis interacts with our systems. These receptors are part of the endocannabinoid system, which helps manage things like appetite, mood, pain, and memory. Here’s a simple breakdown:

  • CB1: Found mainly in the brain and central nervous system, but also in some nerves and organs. It plays a big role in how cannabis affects your mood and mind.
  • CB2: Located in immune system cells and other areas of the body. It’s more about physical effects and can help with inflammation.
  • TRPV1: These are in your bones, skin, tongue, kidneys, and stomach. They’re involved in pain and temperature regulation.
  • TRPV2: Found in muscles, skin, kidneys, and other organs. Similar to TRPV1, they help with sensing pain and body temperature.
  • TRPV3: Present in skin sensory neurons that respond to specific temperatures. They play a role in skin sensation.
  • GPR119: Present mostly in the pancreas and intestines, helping with metabolism and digestion.
  • GPR55: Found in the bones and brain and may help with bone health and brain function.
  • GPR18: Mostly in the immune system and lymph nodes, with a smaller presence in bone marrow and the testes. It plays a role in immunity and inflammation.

Each of these receptors contributes to how cannabis affects your body, targeting different areas based on what you need. This system is why cannabis can help with a range of issues, from pain to appetite to mood.

Contact us

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in office visit or telemedicine.


  • Houston Texas
  • 9597 Jones Road
  • Houston TX, 77065

  • San Antonio Texas
  • 1533 Austin Highway
  • San Antonio TX, 78218